Compounded medications are not FDA approved. FDA does not review compounded medications for safety, effectiveness, or quality before they are marketed.

Reference

Microdose GLP-1 glossary

Dose concepts, formulation, pharmacy, and pricing terms — defined precisely.

This glossary defines the dose concepts, formulation terms, pharmacy classifications, and pricing terms used across the site, so a 'microdose' is never confused with a starter dose, and 'units' are never confused with milligrams. Definitions reflect FDA usage and standard pharmacy practice.

FDA-labeled starter dose
The specific low initial dose in an FDA-approved product's prescribing information, used at treatment initiation to improve tolerability before titration.
Lower-than-maintenance dose
Any dose below a product's labeled maintenance dose, whether during titration or deliberately held below maintenance.
Reduced maintenance dose
A maintenance dose intentionally set below the maximum studied/labeled maintenance dose after a response is achieved.
Slower titration
Extending the time spent at each dose step during dose escalation, usually to manage side effects.
Less-frequent dosing
Administering a dose at longer intervals than labeled (e.g., beyond weekly for a weekly product).
Tapering / off-ramping
Gradually reducing dose or frequency when discontinuing, as opposed to abrupt stopping.
Provider-defined 'microdose'
A marketing/program term used by a telehealth provider for a low-dose plan; definitions vary by provider and are not standardized.
Compounded individualized dose
A patient-specific dose prepared by a compounding pharmacy under a prescription; not an FDA-approved product.
Oral, sublingual, buccal, ODT, or troche product
Non-injectable formulations. One approved oral semaglutide exists (Rybelsus); compounded oral/sublingual/ODT products are separate and unproven.
Standard compounded injection
A compounded injectable at a conventional (non-reduced) dose; not FDA approved.
FDA-approved branded product
A manufactured, FDA-approved GLP-1 (e.g., Wegovy, Ozempic, Zepbound, Mounjaro, Rybelsus) with reviewed manufacturing and labeling.
503A pharmacy
A state-licensed pharmacy compounding patient-specific prescriptions; not FDA-approved manufacturing.
503B outsourcing facility
An FDA-registered facility that may compound in larger batches under CGMP; registration is not product approval.
Beyond-use date (BUD)
The date after which a compounded preparation should not be used; usually much shorter than a manufactured drug's expiration.
Units vs milligrams
Insulin-syringe 'units' measure volume, not drug quantity; the milligrams delivered depend on the concentration.
Effective monthly cost
Total mandatory spend (medication, membership, fees, shipping) divided across the months supplied — the comparable cost figure.

Not medical advice. This page is consumer education, not medical advice, and does not recommend a dose, product, or provider. Compounded medications are not FDA approved. Talk with a licensed clinician about your situation.